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Next generation therapeutics
Creating the next generation of therapeutics
澳门葡京赌博游戏正在不断推动科学的发展，以提供改变生活的药物，这些药物将对澳门葡京赌博游戏致力于治疗的疾病产生最大和最快的影响, prevent, modify and in the future, even cure. 只有加强澳门葡京赌博游戏对疾病生物学的理解，发现针对疾病驱动因素的新方法，澳门葡京赌博游戏才能在肿瘤学的主要治疗领域创造下一代治疗方法, Cardiovascular, Renal and Metabolism, and Respiratory and Immunology.
We are already leveraging the rapid advancements in science and technology to create new therapeutics, such as cell-based therapy, antibody therapeutics, and nucleotide-based therapeutics, for disease mechanisms which were previously considered difficult, if not impossible, to target.1 Additionally, we are working on integrating knowledge of drug candidates and their interactions with their target, 疾病的病理生理学和给药系统，以便设计先进的给药技术.2 Each new insight and every new piece of information brings us closer to creating better, more advanced and more effective treatments for patients.
与世界各地的合作者合作，正在帮助澳门葡京赌博游戏的科学家开拓药物发现的新方法. In fact, 30% of our early pipeline now consists of new drug modalities including oligonucleotides, mRNA and Anticalin® proteins.
Small molecules
Antibody therapeutics
Peptide or protein therapeutics
Peptide or protein therapeutics
Through our long-standing expertise in protein engineering, we are advancing both conventional and novel classes of protein and peptide therapies. Because proteins are large molecules, 它们通常不具有细胞渗透性，传统上仅限于细胞外靶点和注射给药途径. Peptides constitute a smaller format of protein therapeutics. They are typically developed as small, specific and highly selective ligands for extracellular targets.
Through various collaborations, 澳门葡京赌博游戏不仅在探索开发传统的蛋白质疗法和多肽，而且还在探索潜在的创新疗法，如antialin®蛋白质和双环肽. Click the tiles below to read more about these novel drug modalities.
Nucleotide-based therapeutics & gene therapy
Nucleotide-based therapeutics & gene therapy
Recent advances in genomics has led to a myriad of potential new drug targets and with it, the opportunity for nucleotide-based therapeutics to have a real impact on disease. 澳门葡京赌博游戏正在探索一些基于核苷酸的方式，从寡核苷酸和基于rna的治疗到使用CRISPR/Cas9作为潜在的治疗工具. Click the tiles below to read more about these novel drug modalities.
Meet some of our pioneers of next generation therapeutics
Behind every advancement we make, there is a team of dedicated scientists. Find out more about some of our researchers working at the cutting-edge of drug discovery:
References
1. Valeur E, Guéret SM, Adihou H et al. New Modalities for Challenging Targets in Drug Discovery. Angewandte Chemie. 2017. 56(35): 10294-10323.
2. Ashford M. Drug Deliv Transl Res. 2020 Oct 6. doi: 10.1007/s13346-020-00858-6. Online ahead of print.
Collaborate with us
We know that however innovative our science, however effective our medicines and delivery, to achieve all we want to achieve, we cannot do it alone.
Veeva ID: Z4-58111
Date of preparation: September 2023